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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eae2991dd6fff06b1f0e1d83583ef41f5ed3360865876c45cd1b4e51197ec8a' 
  AND token = 'nmFAARsA1gDs91mLC3S3sZe1ud6tCLjZ76IV+34sTD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}