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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c86a5a08d551fc0d050d85684172db0e97a91710ce2a27f4aeecdb6c803aef38' 
  AND token = 'OFgr01Y6Q4KKjOaJr9yWf5x3G/nVlavgm+t0abe3BSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}