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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416e8df0521966a665f291e0209ba5f3ed2e8445b9b6df2965d3479f3cdfcc47' 
  AND token = 'W8kQM1AZd2zgl1vrk4AbMqnK517jCHec/oXDIhTh3nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}