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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb42b2ad16822cbf3409e03dcc184c433712dc74c9d56b5edb4003808ad4982' 
  AND token = 'Zm+vZeeQ9EBQza9qcGBQmd0jPD9l2NyZ4CUjRw+I4wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}