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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c7e0cd0dfb91a8e43cf8e868ff268814628ffc87e09a20fce7453c734142fe' 
  AND token = 'R7eE91jeaSaLt4EFOvT+F42GO46P4f4MKQADei7UNpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}