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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fac49ff0359046a246a1ba1f5a602642f6f405273a3ee840a856856435b91fd' 
  AND token = 'O9GL7tVkWEMNBVYEH/dUSqrl/MOnnLt87RI+hx20zYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}