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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75236d1185e0dc1ca6e1a80b5861b8e127c69121fce449de2767a74054f48cf2' 
  AND token = '+nKkpIDkymimScEvJxUIJlQa5Jn28n8UmIdRQMi64EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}