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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458311311ae0f5099156772b650e6e5493b87706041d166a403eb60bed5b4271' 
  AND token = 'PuqDhZpw0DwBq56GfbPHE6B6UZG5xNEgoDZVl43I3Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}