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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb21236c7e6d998d3830904dfaa6c60e226e45e53bc8d4a529316ee67385d49' 
  AND token = 'Twpu4rX8ssXiLv4QFm71oOY1OSiGMATOL3Ou5M8V6dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}