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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543fdf2bc910a7cfae35896b818fdb3a1db3b6a83fbfd481d7ea1f9248cffafb' 
  AND token = '6+MbNoIWyQS/dtZ4019g/+32s1ChVXGFZdmV164lKMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}