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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb42e2c19de3392a07593704f0a82b6d1d1ac041ea9d38f986e2187020d4d6bc' 
  AND token = 'u/e76XAp2GWMTlirT2kH2UpOcbUgGMfql08q4tJUkMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}