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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510989ee152f55a5f4ad76f158b37674f9bd02ed31b7ed6c3c31460261f3e24f' 
  AND token = 'ixB/TqifmDsqHKRciqi5hKiRz8p0yY8ev3hVzCpqeUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}