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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc49e7887528fb627c636767868678be8729e1ba485b0c4ccbfb9098c0beff1d' 
  AND token = '6+sMMgZRpaaGIN/6UZfWgFckaXA1Q72G0MogFkw1lcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}