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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2dffa36f049f47fa9b9c9833b6d85ef8de22b30ba7a02bf93b0f131524aade' 
  AND token = 'Y+tK+NXrHuOzTM8+6NT/zYwi3ssHAXZALYNjMt0No8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}