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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21153b30d8db15106d9030978214ca07a280b4b94216f0742881ed4f6f097682' 
  AND token = 'Zy3cF51BaTe09KhneRSjqcJOBPSNKLnVlIf3NA8AP/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}