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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5100861e38917bae744eb9be8daa4e26a6e35e371d6a3d38898fc323481bdd3' 
  AND token = 'fQoTtCnREKMxue3+eR4BANH6kVxkmT/jgiC3xOxCqQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}