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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daa538214d6c52ff253860e3920bfd40f4bd75f3d7657bb6a27ed4283d3fa492' 
  AND token = 's3nGW6pEUhrsrneE+YnFTPFJJft7E1366+l0bueofqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}