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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82428c883f6f9c2875a130b3d86e329aa108e9d69f151c0499c8033fab2a8cbe' 
  AND token = 'wGUGIFLlAjc0W54IFYZpoJONO8gCR6SjzZW4eoHhcNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}