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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea0c130b556cfa39be9d5cf6ab5e6eea90933a24f22aefafe41332b0a4a45de' 
  AND token = 'BUW9UB2ZtC4+2KneDs2NwxGhz6UhW8JPxCuKOM+h5DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}