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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005e3b1d5523b354f7a945ed736e7b1901d4cb10e37f6428880e13268dc90210' 
  AND token = 'Mugr1VQ2Z9PpjrkSgT6O+bdSMf1tn1w16wZcfBfQbLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}