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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1637933999dcc136ca7fd0c914ba3bc1f59640c4f520a3c426ce2703527b0068' 
  AND token = 'dGE/unTPC7KzaMda/iO1IQS1L43XIWRD2nZMEGYocKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}