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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c3968016c00199fc85729fb9eed1a8a5b85c83f195b66f4c5f79dc58ba4a3b' 
  AND token = 'V2i0yE/9I8OU67HhLlS4IDZRDlcfKBpyeMnsMtBQqRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}