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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e0b9e1048cd66707d72aabd34858c6cdf5352ea890c1d2d2943330c65a9a50' 
  AND token = 'RRfcbxOrI8UFNel/BfgPGZ9CyqL0UC2gIf10mMsxi8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}