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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fea0dc79b55921d331b1d581752cc1aa6b77ded346eb7675e29859d2f3f5ec6' 
  AND token = 'tgUFWfoPwb8K5trf/CTNVfyfJ2FcnWWIuBGvR+eDgmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}