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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29158d8eda0a13440255705874c57d5558b3e87d1fb671513b58d60866361299' 
  AND token = 'mKXIz3pgAgubTgQeHzS47edu21qwspP1qQFoWy7gO40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}