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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c9d3b372b530335afec443a3e74d51eba55e4ba7288c264978286f40f895d23' 
  AND token = '/Khj8TniR5jI01mmeHNf6jfMPCXaFzsaGDbjbrKn+PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}