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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d67db7e70a7bf8b4ed4dfdb8fe35c7234fde252b01c4374e33696b0aa2648b5' 
  AND token = 'l1WV+QrRIbMvuxTyrUQH2sVA7ddVxP4RSCEVf9F27DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}