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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21934b6bf443bc4098a934141abb7e02ba454aeb596b7a7ad135ee09cf69f463' 
  AND token = 'g8qbfAabDnFMosXy0nW9MYPJGdB/Y40vMRfCy1dNj6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}