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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb49e7de9700e33d124050587d592f7e0c7152bbbb30a537a223a61632c30258' 
  AND token = 'hKpHsDBDXTq42BXbcS9i68fmo/njo22c5ewzte365nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}