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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6fea4d674e9ba477604bb149cd09a906b8ba9867f8511236977a2fc5fb5d97' 
  AND token = 'igIWrmuGjjM9F/WuKyv7WdNj7F+FHSowzv9WdCeQ8a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}