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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e7d139f76add43c1287243cde3b040540c3a2beab4ab412a6eb91eb21acdf9' 
  AND token = 'T4pE7OSWqV1nKX5IPfdpFkoB8pILTXRDEgfNCajQ0yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}