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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460c70db52ec19fabc373661327c6d628a3205b3068fbba876fdc0f0ffe309a6' 
  AND token = '0Y9DhXrbPLDMT+GTb9QLiczn3U5lY56MhsHYMQZQcQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}