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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02b61c2c29dde2cf9c20751e7c143a1c738f9993bc7a4ca88470b6c2fbcc54ab' 
  AND token = 't9E3qAwdckrWkxbcCtuU5jcGTTUN0tGhAW0T3qIQTQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}