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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4d7d49318907685965f861beb30b8101e8a0f098ebf8c5f9cd3c18de5a8206' 
  AND token = '8zq7tAjsLPtlI1/xKOoZZcVEt1MkI22DZ+IPyKLkbD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}