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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05af4bb388d5aca9621a2f1b6993860e787e7d2ff202f52e95c1fc95eaaa3438' 
  AND token = 'G/tdJ8jtnrqzMbUWzUkDF0o3QUbGJZ5jCZRipsDGcgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}