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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1622cb8a8b0dcad67ec0801b4a295ad517fce33cf2cb6f5d30da558ef8035b80' 
  AND token = 'hkgWCvoU76iJAAxlouaCXCGeHN2mAnQuq0ABB/O8xZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}