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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a340cacc3fc30b3636cbe4f248a1446ead8de7c9b1ecb12ec2faaec64ab9d61' 
  AND token = '3bNMNDJl8m66cR9/YV+CUjd+mRxLjTkpXk3jcug3LpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}