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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecdf8a9f6cd085bf3d6f421cbc3464214c959a12e9f1838123b56fd1b1b7dd91' 
  AND token = 'AK6RmPUPBwxF0PS4H8AdPuuPEV4nK47ei8ffjWz1HYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}