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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d9fc7b183c7ca9bc361798bdb2baff3b0c2568d944a6333d2f6e3d28a9504e' 
  AND token = 'uyDCq3RpLkALB4bSX2RP7uTP0xoMCCEVt2Izw7XH0vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}