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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2831be08a587dfc29ee251075cc74f6f44de2b418dc844c25ba1801be5ea9c' 
  AND token = 'Z4RpwiWTwLCUNbf8k5f+aavFw7DUUqZvu+66TbZtTuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}