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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd20bce18449ff981f143e5c9072f533f1b88809d7584b99d0ffb30b0b80eeb' 
  AND token = '9S9pUFg0q4uGDEXN2JjLejO51L4exC5vi3owwLjewJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}