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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3d680039e6229da0351941d01940adc64caa2f5bc3f0ccf14317cac954c8cc' 
  AND token = 'lzr/9rOmrO4XG9FFAtq2qYUaeiwSiWJRSrG1OYZ7oV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}