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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270530046446db2d6e7eaa6e2a42230ec104637d4c5f3e9836841eb862c60848' 
  AND token = 'h6kOvsy7uK+m1bsmOUtp4uRkIkmStjrfjM0YG5OoeFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}