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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa300bf4a1f24dce17e02f1c8929d0a1d2cf4cba4bb193af4c2b32bc82596858' 
  AND token = 'fHT34uc+iRhml8LxDZRgHaSEBDPyhkO6VrhtXVu4AWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}