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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665ca442c31fe326eaff84a74a005778e4ed661650dc8e64d8611a4d2c472eca' 
  AND token = '108NDeTHxTaR7kYL+6C1lu237V0l9Unt/01BGdot4fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}