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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8ba73fddd693c796d10039c01d1f8cedaa1d8deca296476b69396da0725fd4' 
  AND token = '9XRxR66N9Y3OCEDi3+4oqyGD/AVYfltz1w9QvwPWS+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}