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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52302c33d8afd498702442c1e79b27357c2c153c52577e94e46828fa9e0834ce' 
  AND token = 'Hg+RBvbLoCRu5e2ffeiQrAV7xnKVYROoA/aAjdQ5Y6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}