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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a7ea0178b324ccd6b2aa73e49ae3bf0466889c70a99d9d2e84196d85c64129' 
  AND token = 'N7ICfPCrijC99SKTn7opy6iNMmC37bU9z3koj3IjwwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}