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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc3a55ba82fb7621326557001344ee7f227cf6f0d8567303a7f063bcdc5e8ec' 
  AND token = 'IAvRxMCWf3Ld+d7w7LMkNTTwUo1BLSBQrRuWRMn2tPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}