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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268edc723aca360b4bad6ab27e4a8d41f27f6cca132a363836e4b94d01b87489' 
  AND token = 'L2Vzs4DOWy9r05G+gtWqxJMsbOXJt2ZcOcU4PRenFQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}